Time 4 Joint Pro

TIME 4 JOINT PRO | High Strength Joint Protection Supplement

Exercise can provide many benefits for our joints, such as increased strength and mobility, but over time, the activities of daily life can lead to ‘wear and tear’ that may result in inflammation, pain, and stiffness.

Our Joint Protection Supplement contains 16 active ingredients including Glucosamine and Chondroitin in specific ratios to help support bone, joint, cartilage and connective tissue health.

• 16 Active Ingredients
• High Strength Joint Protection Supplement
• 30 Days Supply

Here is a brief rundown of what is contained within our Joint Protection Supplement.

GLUCOSAMINE HCI: Glucosamine aids joint health in a several ways. For example, it plays a vital role in the production of hyaluronic acid. This a naturally occurring substance found in and around joints, which has been shown to provide several benefits including managing inflammation, lubricating and cushioning joint cartilage and preventing its breakdown. There are several types of Glucosamine. The most common are Glucosamine Hydrocholoride (HCI) and Glucosamine Sulphate. Glucosamine HCI is a more concentrated form of Glucosamine than Glucosamine sulphate. It also has less sodium, is more naturally stable and is derived from vegetable sources.

CHONDROITIN SULPHATE: Numerous studies have shown the clinical benefits of Chondroitin Sulphate for decreasing pain, improving functional disability, reducing non-steroidal anti-inflammatory drug (NSAID) consumption with good tolerability.

THE BENEFITS OF COMBINING GLUCOSAMINE HCI AND CHONDROITIN: Our Joint Protection Supplement contains both Glucosamine and Chondroitin. A combination of Glucosamine HCI and Chondroitin Sulphate have been shown to reduce joint space narrowing.  When joints are healthy, they show normal spacing where the bone ends meet. However, narrowing of the joint space may result from overuse of joints and wear and tear wear. Being overweight and having muscle weakness also contributes to joint space narrowing.

TURMERIC / CURCUMIN: There is a considerable body of research to support the use of Turmeric in the treatment of joint pain. Studies have shown an improvement in pain, physical function, and quality of life after taking Curcumin. They also reported reduced use of pain killers and side effects during treatment and that it can help to prevent the breakdown of joint cartilage.

Note: Ingesting Curcumin by itself does not lead to the associated health benefits due to its poor bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. There are a number of substances that can increase bioavailability. Time 4 Joint Pro contains Piperine for this purpose. This is the major active component of Black Pepper and, when combined with Curcumin, has been shown to increase its bioavailability by up to 2000%.

GINGER ROOT EXTRACT: Ginger possesses the potential to prevent and manage several diseases, including those effecting the joints and it can provide significant reduction in pain and disability. Interestingly, one study also noted that Ginger can help to reduce delayed onset muscle soreness (DOMS), such as that caused by exercise.

PIPERINE: Studies have found that Piperine has anti-inflammatory and pain-relieving effects. Piperine can aid detoxification, and enhancement of the absorption and bioavailability of herbal and conventional drugs and has been found to have immune modulating, antioxidant, anti-inflammatory properties.

CALCIUM: Chronic Calcium deficiency resulting from inadequate intake is one of several important causes of reduced bone mass and osteoporosis. Therefore, it is vital that adequate dietary Calcium is consumed at all stages of life and particularly in early life so that the genetically programmed peak bone mass can be reached and in later adulthood so that the skeletal mass can be maintained, and age-related bone loss minimised. Unfortunately, there is evidence that many individuals are not consuming the recommended levels of Calcium in their diet. Furthermore, it is not only the amount of Calcium in the diet but also its absorption by the body which determines the availability of Calcium for bone development and maintenance. To help address this, Time 4 Joint Pro contains Vitamin D and Vitamin K, as they play a valuable role in helping to ensure that we absorb sufficient levels of Calcium and that it is directed to where it is needed in the body.

VITAMIN D: Although we can obtain Vitamin D from various foods and our bodies can produce it from sunlight, approximately half the UK population suffer from Vitamin D deficiency during certain times of the year, which has implications for our bone and joint health. Studies have found that moderate Vitamin D deficiency independently predicts the incidents, or worsening of, knee and hip pain. Therefore, the authors suggest that correcting Vitamin D deficiency may attenuate worsening of these conditions.

VITAMIN K: Various reviews have highlighted the link between low Vitamin K levels, joint pain and cartilage degeneration. Specifically, it has been shown that Vitamin K deficiency produces abnormal growth plate calcification and inappropriate mineralisation of cartilage leading to osteoarthritis. On the other hand, the current literature generally agrees that a sufficient level of Vitamin K is associated with a lower risk of osteoarthritis and pathological joint features. Consequently, these findings have led to several authorities to recommend that we ensure a sufficient intake of Vitamin K to protect our joints.

VITAMIN C: Studies have evaluated the effects of Vitamin C on collagen production and ability to form chemical bonds. It was shown that Vitamin C induced a dose-dependent increase in collagen type I deposits, the type of collagen found in bone and tendons and that participants in the study receiving additional Vitamin C reported a better quality of life and a reduced use of pain killers.

VITAMIN E: Vitamin E enhances the growth of cartilage producing cells and exhibits anti-inflammatory activity, as well as playing an important role in the prevention of cartilage degeneration. It acts as an antioxidant, helping protect the body from free radicals, which are compounds that can damage the body

ZINC: Studies have investigated the effects of Zinc on bone cell production. The results of the study showed that Zinc can increase the formation of bone by stimulating cell proliferation and collagen synthesis in bone building cells.

MANGANESE: The results of a review have shown that manganese, along with Copper, and Zinc, is essential for bone metabolism. The results further demonstrated the effectiveness of Calcium, Copper, Manganese and Zinc supplementation on spinal bone mineral density and the necessity of trace elements for optimal bone matrix development and the maintenance of bone density.

COPPER: Copper, along with Manganese and Zinc, are essential for bone metabolism and Copper has been shown to help reduce inflammation. Despite the importance of Copper being recognised for a nearly a century, it has been decreasing in the Western diet with half of the adult population consuming less than the amount recommended in the United Kingdom.

FOLIC ACID: Studies have found that Folic Acid supplementation has a positive effect on the rate of bone metabolism and can improve joint mobility and help to relieve joint pain. Observational studies suggest a link between low folate levels and risk of inflammatory disease.

SELENIUM: Selenium deficiency is associated with biochemical impairments that can result in cartilage damage and can contribute to various diseases including osteoarthritis. A sufficient quantity of Selenium has been shown to contribute to the management of complications of autoimmune diseases, which may be due to the anti-inflammatory effects of Selenium.

VITAMIN B12: Low Vitamin B12 is associated with lower bone density, which increases the risk of osteoporosis and fracture. Both men and women with low Vitamin B12 concentrations have lower average bone density than those with higher Vitamin B12 levels. Vitamin B12 and Folic Acid deficiency are associated with a higher serum concentration of homocysteine, which is a risk factor for fractures. The latest information on Vitamin B12 for the treatment of pain conditions concludes that studies support multiple beneficial effects of Vitamin B12 including the regeneration of nerves and the inhibition of pain-signalling pathways while clinical trials provide evidence for the effectiveness of Vitamin B12 for the treatment of low back pain and pain due to nerve damage.

MANUFACTURED IN THE UK – Time 4 Joint Pro our Joint Protection Supplement was developed in the UK by a team of professionals from the fields of nutrition, biochemistry & exercise with decades of industry experience & is manufactured in a BRC, ISO & GMP accredited facility to give you complete peace of mind. We employ an evidence-based approach to all our products & provide access to peer-reviewed research papers from some of the leading scientific journals to support their use. A full explanation of all technical terminology is provided so that you fully understand exactly what is contained within our supplements & the potential benefits for health & performance they may provide you with. While many of our products are aimed at increasing muscle size & strength & reducing body fat, we also understand how important your health is & have developed various supplements that promote general health & well-being to enable you to become the best you can be.

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Nutritional Table For Joint Protection Supplement