SCREENING OF ANTISTRESS PROPERTIES OF CHLOROPHYTUM BORIVILIANUM TUBER

Deore and Khadabadi

Summary

 Chlorophytum borivilianum belonging to family liliaceae is a very famous for its adaptogenic, immunomodulatory properties in traditional Indian system of ayurveda. In recent era there is a great thrust on screening of herbal extracts and formulations for Adaptogenic action as stress is a daily phenomenon faced by every human. The aim of the present study is to investigate the antistress activity of Aqueous and alcoholic tuber extracts of Chlorophytum borivilianum. This property is assessed by swim endurance stress, anorexic test in rats and despair swim test. Cold stress induced Gastric ulceration model was also selected to evaluate antiulcer activity. The effect of single oral dose of the extracts was evaluated at 30, 100 and 300 mg/ kg. It was found that alcoholic extract significantly increases swimming time and reduces the ulcer index compared to that of control group. A significant effect (p< 0.001) from 200 mg/ kg dose for both the extracts was observed in all four models.